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Gene Expression Literature Summary
Assay
Age
In situ RNA (section)
10.5 DPC

16 matching records from 16 references.

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Kdr  kinase insert domain protein receptor   (Synonyms: Flk1, Flk-1, orv, vascular endothelial growth factor receptor- 2, VEGFR2, VEGFR-2, VEGF receptor-2)
Results  Reference
1*J:68214 Dor Y, Camenisch TD, Itin A, Fishman GI, McDonald JA, Carmeliet P, Keshet E, A novel role for VEGF in endocardial cushion formation and its potential contribution to congenital heart defects. Development. 2001 May;128(9):1531-8
1*J:118798 Fan B, Brennan J, Grant D, Peale F, Rangell L, Kirchhofer D, Hepatocyte growth factor activator inhibitor-1 (HAI-1) is essential for the integrity of basement membranes in the developing placental labyrinth. Dev Biol. 2007 Mar 1;303(1):222-30
1J:89444 Fischer A, Schumacher N, Maier M, Sendtner M, Gessler M, The Notch target genes Hey1 and Hey2 are required for embryonic vascular development. Genes Dev. 2004 Apr 15;18(8):901-11
1J:99584 Hitz C, Vogt-Weisenhorn D, Ruiz P, Wurst W, Floss T, Progressive loss of the spongiotrophoblast layer of Birc6/Bruce mutants results in embryonic lethality. Genesis. 2005 Jun;42(2):91-103
1J:141347 Muthig V, Gilsbach R, Haubold M, Philipp M, Ivacevic T, Gessler M, Hein L, Upregulation of soluble vascular endothelial growth factor receptor 1 contributes to angiogenesis defects in the placenta of alpha 2B-adrenoceptor deficient mice. Circ Res. 2007 Sep 28;101(7):682-91
1J:22847 Qin Y, Sato TN, Mouse multidrug resistance 1a/3 gene is the earliest known endothelial cell differentiation marker during blood-brain barrier development. Dev Dyn. 1995 Feb;202(2):172-80
1J:186931 Saito Y, Kojima T, Takahashi N, Mab21l2 is essential for embryonic heart and liver development. PLoS One. 2012;7(3):e32991
1*J:259970 Segerer G, Hadamek K, Zundler M, Fekete A, Seifried A, Mueller MJ, Koentgen F, Gessler M, Jeanclos E, Gohla A, An essential developmental function for murine phosphoglycolate phosphatase in safeguarding cell proliferation. Sci Rep. 2016 Oct 12;6:35160
1J:144155 Shin D, Anderson DJ, Isolation of arterial-specific genes by subtractive hybridization reveals molecular heterogeneity among arterial endothelial cells. Dev Dyn. 2005 Aug;233(4):1589-604
1*J:86366 Soncin F, Mattot V, Lionneton F, Spruyt N, Lepretre F, Begue A, Stehelin D, VE-statin, an endothelial repressor of smooth muscle cell migration. EMBO J. 2003 Nov 3;22(21):5700-11
1*J:166614 Stankunas K, Ma GK, Kuhnert FJ, Kuo CJ, Chang CP, VEGF signaling has distinct spatiotemporal roles during heart valve development. Dev Biol. 2010 Nov 15;347(2):325-36
1*J:50513 Steingrimsson E, Tessarollo L, Reid SW, Jenkins NA, Copeland NG, The bHLH-Zip transcription factor Tfeb is essential for placental vascularization. Development. 1998 Dec;125(23):4607-16
1J:163273 Stemmler MP, Bedzhov I, A Cdh1HA knock-in allele rescues the Cdh1-/- phenotype but shows essential Cdh1 function during placentation. Dev Dyn. 2010 Sep;239(9):2330-44
1J:156412 Tunster SJ, Tycko B, John RM, The imprinted Phlda2 gene regulates extraembryonic energy stores. Mol Cell Biol. 2010 Jan;30(1):295-306
1J:132526 Unezaki S, Horai R, Sudo K, Iwakura Y, Ito S, Ovol2/Movo, a homologue of Drosophila ovo, is required for angiogenesis, heart formation and placental development in mice. Genes Cells. 2007 Jun;12(6):773-85
1J:104372 van Nes J, de Graaff W, Lebrin F, Gerhard M, Beck F, Deschamps J, The Cdx4 mutation affects axial development and reveals an essential role of Cdx genes in the ontogenesis of the placental labyrinth in mice. Development. 2006 Feb;133(3):419-28

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory